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CASE REPORT
Year : 2020  |  Volume : 58  |  Issue : 4  |  Page : 307-309

Skin lesions over the neck with vision loss: Pseudoxanthoma elasticum with angioid streaks


1 Department of Vitreo-Retina, ASG Eye Hospital, Varanasi, Uttar Pradesh, India
2 Department of Vitreo-Retina, Aravind Eye Hospital, Madurai, Tamil Nadu, India

Correspondence Address:
Dr. Gauri Khare
ASG Eye Hospital, Varanasi, Uttar Pradesh
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/tjosr.tjosr_65_20

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Pseudoxanthoma elasticum (PXE) is an autosomal recessive multisystem disorder characterized by the involvement of skin, cardiovascular system, and the eyes. Angioid streaks (AS) are the most common ophthalmoscopic finding in PXE. Choroidal neovascular membrane (CNVM) is the most severe sight-threatening ophthalmic complication associated with AS in PXE. Prompt ophthalmologic referral, early diagnosis of CNVM, and appropriate therapy with intravitreal injection of antivascular endothelial growth factors are crucial to preserve the vision of patients of PXE with AS-associated CNVM. In this short case series of three patients, we describe different forms of retinopathy in PXE and their management.


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