• Users Online: 186
  • Print this page
  • Email this page
CASE REPORT
Year : 2021  |  Volume : 59  |  Issue : 4  |  Page : 396-399

Bilateral demyelinating optic neuropathy with retinal pigment epithelial mottling and concurrent central serous chorioretinopathy due to the domino effect of severe Vitamin B12 deficiency


1 Medical Officer, Department of Cataract and Refractive Surgery, Mahathma Eye Hospital Private Limited, Tiruchirappalli, Tamil Nadu, India
2 Medical Officer, Department of Glaucoma and Research, Mahathma Eye Hospital Private Limited, Tiruchirappalli, Tamil Nadu, India
3 Chief Medical Officer, Department of Cataract and Refractive Surgery, Mahathma Eye Hospital Private Limited, Tiruchirappalli, Tamil Nadu, India
4 Head of the Department of Cataract and Refractive Surgery, Mahathma Eye Hospital Private Limited, Tiruchirappalli, Tamil Nadu, India
5 Medical Officer, Department of Vitreo-Retinal Services, Mahathma Eye Hospital Private Limited, Tiruchirappalli, Tamil Nadu, India
6 Optometrist, Mahathma Eye Hospital Private Limited, Tiruchirappalli, Tamil Nadu, India

Correspondence Address:
Dr. Prasanna Venkatesh Ramesh
Department of Glaucoma and Research, Mahathma Eye Hospital Private Limited, No 6, Tennur, Seshapuram, Tiruchirappalli - 620 017, Tamil Nadu
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/tjosr.tjosr_33_21

Get Permissions

A 35-year-old female presented with severe headache and left-sided hemifacial spasm to the ophthalmic outpatient department. Ocular examination revealed normal visual acuity and color vision, with a presumably normal posterior pole in OU, except for parafoveal central serous chorioretinopathy (CSCR) in OD. Infrared imaging of both fundi revealed generalized retinal pigment epithelial (RPE) mottling, despite the color fundus appearing apparently normal in OU. Complete history taking, systemic workup, and hematological workup was performed and was normal, except for severe Vitamin B12 deficiency. Visual evoked potential was performed and showed delayed latency in OU, diagnosing subclinical demyelinating optic neuropathy. The patient was then started on methylcobalamin 1500 mcg and was reviewed. Signs resolved completely at 1 month follow-up. RPE disturbance (due to severe Vitamin B12 deficiency) may be a possible indirect contributor for CSCR. Hence, Vitamin B12 deficiency manifesting as bilateral optic neuropathy with extensive RPE mottling should be closely monitored for the evolution of CSCR.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed248    
    Printed0    
    Emailed0    
    PDF Downloaded12    
    Comments [Add]    

Recommend this journal