|Year : 2021 | Volume
| Issue : 4 | Page : 416
Limbal dermoid in Goldenhar–Gorlin syndrome
Vijayalakshmi A Senthilkumar
Department of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu, India
|Date of Submission||25-Mar-2020|
|Date of Decision||10-Apr-2020|
|Date of Acceptance||21-Apr-2020|
|Date of Web Publication||21-Dec-2021|
Dr. Vijayalakshmi A Senthilkumar
Department of Glaucoma, Aravind Eye Hospital and Postgraduate Institute of Ophthalmology, Madurai, Tamil Nadu
Source of Support: None, Conflict of Interest: None
|How to cite this article:|
Senthilkumar VA. Limbal dermoid in Goldenhar–Gorlin syndrome. TNOA J Ophthalmic Sci Res 2021;59:416
We report a case of a 40-year-old male presented to us with limbal dermoid in the left eye [Figure 1]a and [Figure 1]b. Systemic examination revealed preauricular tags and vertebral anomalies. Goldenhar–Gorlin syndrome or oculo-auriculo-vertebral dysplasia is a rare congenital malformation of the structures developed from the first and second branchial arches during blastogenesis period of embryo formation (30–45 days of intrauterine life). The incidence has been reported to be 1:3500–1:5600, with a male-to-female ratio of 3:2. Limbal or epibulbar dermoids occur in 35% of cases and appear as pale-yellowish solid mass lesions with hair shafts. Most often, it is located at the lower temporal limbus involving the conjunctiva and cornea and contains cellular elements from ectodermal and mesodermal origin such as hair follicles, sebaceous and sweat glands, ectopic lacrimal gland, and cartilage. Surgical excision of the dermoid depends on multiple factors such as original size, rate of growth, secondary corneal defect/dellen, and psychosocial factors.,
|Figure 1: (a) Clinical photograph of the left eye showing an inferotemporal limbal dermoid in a patient with Goldenhar–Gorlin syndrome. (b) Magnified image of the same showing multiple hair follicles|
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Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient(s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
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Conflicts of interest
There are no conflicts of interest.
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