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Year : 2022  |  Volume : 60  |  Issue : 1  |  Page : 117

Bilateral hyperplastic persistent pupillary membrane: A case-based approach

Department of Cornea and Refractive Surgery, Aravind Eye Hospitals and Postgraduate Institute of Ophthalmology, Anna Nagar, Madurai, Tamil Nadu, India

Date of Submission19-Apr-2021
Date of Acceptance28-Sep-2021
Date of Web Publication22-Mar-2022

Correspondence Address:
Dr. Sarvesswaran Prakash
Aravind Eye Hospital and Post Graduate Institute of Ophthalmology, Madurai, Tamil Nadu
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjosr.tjosr_44_21

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How to cite this article:
Prakash S, Radhakrishnan N, Prajna V. Bilateral hyperplastic persistent pupillary membrane: A case-based approach. TNOA J Ophthalmic Sci Res 2022;60:117

How to cite this URL:
Prakash S, Radhakrishnan N, Prajna V. Bilateral hyperplastic persistent pupillary membrane: A case-based approach. TNOA J Ophthalmic Sci Res [serial online] 2022 [cited 2022 Jun 29];60:117. Available from: https://www.tnoajosr.com/text.asp?2022/60/1/117/340363

Persistent pupillary membrane (PPM) is due to incomplete involution of tunica vasculosa lentis which normally disappears by the end of 8th–9th month of gestation.[1],[2] Dense bilateral hyperplastic PPM is a rare occurrence with high risk of causing amblyopia and cataract in early age.[3],[4] In our case, despite central thick bi-lateral PPM [Figure 1], the patient did not develop amblyopia due to stenopic effect of pseudo-pupillary apertures and was conservatively managed with spectacles. Medical, laser therapy and surgical treatment have been reported early.[4],[5],[6] Ophthalmologists need to recognize this condition early and treat them on individual case based approach.
Figure 1: Thick dense hyperplastic persistent pupillary membrane with multiple pseudo-pupil in right (a) and left eye (b) (undilated view), (c) after dilatation in right eye, (d) retro-illumination view of the left eye

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Declaration of patient consent

The authors certify that they have obtained all appropriate patient consents forms. In the form, patient has/have given his/her consent for his/her/their images and other clinical information to be reported in the journal. The patient understands that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

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Conflicts of interest

There are no conflicts of interest.

  References Top

Duke-Elder WS. Congenital deformities. In: Duke-Elder WS, editor. System of Ophthalmology. Part. 2., Vol. 3. St. Louis: CV Mosby; 1964. p. 775-82.  Back to cited text no. 1
Vega LF, Sabates R. Neodymium: YAG laser treatment of persistent pupillary membrane. Ophthalmic Surg 1987;18:452-4.  Back to cited text no. 2
Ramakrishnan R, Natchiar G, Michon J, Robin AL. Bilateral extensive persistent pupillary membranes treated with the neodymium-YAG laser. Arch Ophthalmol 1993;111:28, 32.  Back to cited text no. 3
Miller SD, Judisch GF. Persistent pupillary membrane: Successful medical management. Arch Ophthalmol 1979;97:1911-3.  Back to cited text no. 4
Gupta R, Kumar S, Sonika U, Sood S. Laser and surgical management of hyperplastic persistent pupillary membrane. Ophthalmic Surg Lasers Imaging 2003;34:136-9.  Back to cited text no. 5
Wojciech O, Maria O. Surgical management of bilateral persistent pupillary membrane. Clin Surg 2019;4:2469.  Back to cited text no. 6


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