• Users Online: 389
  • Print this page
  • Email this page

 Table of Contents  
Year : 2022  |  Volume : 60  |  Issue : 1  |  Page : 118

Nibbled lens: A case of isolated coloboma lentis

1 Department of Retina and Vitreous, Rajan Eye Care Hospital, T Ngara, Chennai, Tamil Nadu, India
2 Department of Opthlamology, Thoothukudi Medical College, Thoothukudi, Tamil Nadu, India
3 Department of Ophthalmology, Chettinad Medical College, Chennai, Tamil Nadu, India

Date of Submission01-Aug-2021
Date of Decision01-Oct-2021
Date of Acceptance07-Oct-2021
Date of Web Publication22-Mar-2022

Correspondence Address:
Dr. M Arthi
Rajan eEye Care Hospital, No. 5, Vidyodaya Second Street, T. Nagar, Chennai - 600 017, Tamil Nadu
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjosr.tjosr_121_21

Rights and Permissions

How to cite this article:
Arthi M, Periyanayagi M, Rajakumari M. Nibbled lens: A case of isolated coloboma lentis. TNOA J Ophthalmic Sci Res 2022;60:118

How to cite this URL:
Arthi M, Periyanayagi M, Rajakumari M. Nibbled lens: A case of isolated coloboma lentis. TNOA J Ophthalmic Sci Res [serial online] 2022 [cited 2022 Jun 29];60:118. Available from: https://www.tnoajosr.com/text.asp?2022/60/1/118/340343

A 23-year-old female came with complaints of defective vision in the left eye (LE) since childhood. She had no significant ocular or systemic history. On examination, the right eye had best-corrected visual acuity (BCVA) of 6/6 and was within the normal limits. LE had BCVA of 6/9 and anterior segment examination showed nasally subluxated crystalline lens with temporal notching, deficient zonules, and subtle phacodonesis [Figure 1]. Posterior segment was within the normal limits. A diagnosis of isolated coloboma lentis was made. Thorough systemic examination including arm span length and cardiovascular examination was normal and ruled out syndromic associations. She was advised glasses in view of good BCVA.
Figure 1: (a) Slit-lamp photograph showing nasally subluxated clear crystalline lens with temporal notching indicated by black arrows, (b) slit-lamp photograph showing areas of deficient zonules indicated by black asterisk

Click here to view

Defective development of the ciliary body and zonules due to failure of closure of fetal fissure during embryogenesis results in release of tension and notching of the lens thereby leading to a lenticular coloboma.[1] It can manifest unilaterally or bilaterally, isolated or in association with retino choroidal coloboma.[2] It is differentiated from subluxated lens by the irregular notched contour of the edge of the lens with deficient zonules. Systemic associations include Marfans syndrome, Sticklers syndrome, and Cohen's syndrome.[3] It may be managed conservatively when the vision is good but may need surgical intervention like phacoemulsification and intraocular lens (IOL) implantation. Scleral fixated or iris fixated IOL implantation maybe required in case of gross subluxation.[4] The surgical intervention is not infrequently complicated by capsular fornix aspiration, extension of zonular dialysis, vitreous prolapse into the anterior chamber, IOL decentration, capsular phimosis, and retinal detachment.[5] The defective development of ciliary body results in abnormal adherence between lens and peripheral retina, thereby causing an increased incidence of retinal detachment in these patients.[6]

Financial support and sponsorship


Conflicts of interest

There are no conflicts of interest.

  References Top

Duke-Elder S. Anomalies of the lens. In: System of Ophthalmology: Normal and Abnormal Development: Congenital Deformities. Vol. 3. London: Henry Kimpton; 1964. p. 706-8.  Back to cited text no. 1
Ilsen PF, Patel S. Coloboma of the crystalline lens. Optometry 2003;74:765-74.  Back to cited text no. 2
Bavbek T, Ogüt MS, Kazokoglu H. Congenital lens coloboma and associated pathologies. Doc Ophthalmol 1993;83:313-22.  Back to cited text no. 3
Nordlund ML, Sugar A, Moroi SE. Phacoemulsification and intraocular lens placement in eyes with cataract and congenital coloboma: Visual acuity and complications. J Cataract Refract Surg 2000;26:1035-40.  Back to cited text no. 4
Wang JK, Ma SH. Lens coloboma treated with lens surgery. BMJ Case Rep 2015;2015:bcr2015210559.  Back to cited text no. 5
Li J, Ma X, Hu Z. Lens coloboma and associated ocular malformations. Eye Sci 2011;26:108-10.  Back to cited text no. 6


  [Figure 1]


Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
Access Statistics
Email Alert *
Add to My List *
* Registration required (free)

  In this article
Article Figures

 Article Access Statistics
    PDF Downloaded31    
    Comments [Add]    

Recommend this journal