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| OPHTHALMIC IMAGE |
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| Year : 2022 | Volume
: 60
| Issue : 1 | Page : 122 |
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Coats uncoated!
Smital Mahadeorao Metange, Syed Mohideen Abdul Khadar
Department of Vitreo-Retina, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India
| Date of Submission | 16-Sep-2021 |
| Date of Decision | 01-Oct-2021 |
| Date of Acceptance | 16-Oct-2021 |
| Date of Web Publication | 22-Mar-2022 |
Correspondence Address:
Dr. Smital Mahadeorao Metange
Department of Vitreo-Retina, Aravind Eye Hospital, S. N. High Road, Vannarpettai, Tirunelveli - 627 001, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/tjosr.tjosr_142_21
How to cite this article:
Metange SM, Abdul Khadar SM. Coats uncoated!. TNOA J Ophthalmic Sci Res 2022;60:122 |
Coats is an idiopathic disease related to the abnormalities in the Wnt signaling pathway during retinal angiogenesis.[1],[2] It progresses through the stages of retinal vascular anomalies, subretinal exudation, exudative retinal detachment, glaucoma, and phthisis. The patient usually is a young male with unilateral decreased vision, strabismus, or leukocoria. The importance lies in differentiating it from retinoblastoma. Treatment options range from observation, photocoagulation, cryotherapy, and intravitreal steroids to vitrectomy and subretinal fluid drainage which are rarely needed. Although the anti-vascular endothelial growth factors have been studied, their role remains inconclusive.[3],[4] In a 4-year young boy on dilatation, we uncoated the total exudative retinal detachment abutting the lens suggestive of Stage 3B of Coats disease on smartphone photography in the left eye [Figure 1]. | Figure 1: Smartphone photographic image of the left eye of a 4-year-old male presenting with diffuse retinal telangiectasias, subretinal exudation, and total exudative retinal detachment abutting the lens suggestive of Stage 3B of Coats disease
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Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form the patient (s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Clevers H. Eyeing up new Wnt pathway players. Cell 2009;139:227-9.  |
| 2. | Robitaille JM, Zheng B, Wallace K, Beis MJ, Tatlidil C, Yang J, et al. The role of Frizzled-4 mutations in familial exudative vitreoretinopathy and Coats disease. Br J Ophthalmol 2011;95:574-9. |
| 3. | Patel NA, Berrocal AM, Murray TG, Villegas VM. Advanced Coats' disease treated with intravitreal brolucizumab combined with laser photocoagulation. Am J Ophthalmol Case Rep 2020;19:100815. |
| 4. | Adeniran JF, Duff SM, Mimouni M, Lambert N, Ramasubramanian A. Treatment of Coats' disease: An analysis of pooled results. Int J Ophthalmol 2019;12:668-74. |
[Figure 1]
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