|
 
 |
| LETTER TO THE EDITOR |
|
| Year : 2022 | Volume
: 60
| Issue : 1 | Page : 132 |
|
Role of eye changes in diagnosis of systemic diseases
Khichar Shubhakaran
Department of Neurology, Dr. S.N. Medical College, Jodhpur, Rajasthan, India
| Date of Submission | 15-Sep-2020 |
| Date of Acceptance | 28-Sep-2021 |
| Date of Web Publication | 22-Mar-2022 |
Correspondence Address:
Dr. Khichar Shubhakaran
House No. E-22/13, Umed Hospital Campus, Opposite Geeta Bhavan, Jodhpur - 342 003, Rajasthan
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/tjosr.tjosr_136_20
How to cite this article:
Shubhakaran K. Role of eye changes in diagnosis of systemic diseases. TNOA J Ophthalmic Sci Res 2022;60:132 |
I read an interesting imaging of Roth spots by Mohan and Rajan published in September 2020 issue (213-4).[1] The authors have highlighted the importance of such finding in clinching to a diagnoses such as bacterial endocarditis, leukemia, and anemia.[1] Here I would like to share my experience and views as under:
- Certain eye changes are well documented and are of diagnostic like in bacterial endocarditis, congenital, and hereditary metabolic disorders.[2] They are also being described in certain infectious diseases such as malaria, dengue, HIV, and cysticercosis.,[2],[3] where in these require to be established as a diagnostic marker in further prospective and retrospective studied
- We studied the ophthalmoscopic abnormalities in adult patients of falciparum malaria and concluded that the ophthalmoscopic abnormalities in malaria had no statistically significant association with poor prognosis except disc pallor, but the patients with ophthalmoscopic abnormalities have a trend of worse prognosis in comparison to those without the changes. We also concluded by analyzing our data that the ophthalmoscopic changes were the reflection of underlying organ dysfunctions such as anemia and renal failure.[3] as the authors pointed out anemia and leukemia[1]
- Similarly, various such eye changes such as Roth spot and other changes were also reported in dengue patients.[2]
- We also found a patient of malaria with vitreous haemorrhage who presented with visual deterioration before losing consciousness so it may be reason of visual impairment in patients of malaria besides optic neuritis acute disseminated encephalomyelitis and cortical blindness[4]
- The detection of such changes is an important bedside tool which help diagnose, narrow down the differentials in a particular clinical setting, i.e. in malaria and dengue in an endemic area, especially with flare up during particular seasons and prognosis.[2],[4],[5]
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Mohan S, Rajan M. Roth spots; a window to underlying conditions. TNOA J Ophthalmic Sci Res 2020;58:231-4.  |
| 2. | Shubhakaran K, Khichar RJ. Nonmydriatic ocular fundus photography among headache patients in an emergency department. Neurology Oct 2013;81(15):1366-1367. doi: 10.1212/01.wnl.000043684.64959.67. |
| 3. | Mehta S. Ocular lesions in severe dengue hemorrhagic fever (DHF). J Assoc Physicians India 2005;53:656-7. |
| 4. | Kochar DK, Shubhakaran, Kumawat BL, Thanvi I, Joshi A, Vyas SP. Ophthalmoscopic abnormalities in adults with falciparum malaria. QJM 1998;91:845-52. |
| 5. | Kochar DK, Shubhakaran, Kumawat BL, Vyas SP. Prognostic significance of eye changes in cerebral malaria. J Assoc Physicians India 2000;48:473-7. |
|
Search Pubmed for