|
 
 |
| OPHTHALMIC IMAGE |
|
| Year : 2022 | Volume
: 60
| Issue : 2 | Page : 203-204 |
|
'Bread Crumbs' of granular corneal dystrophy: Through the looking glass (Scheimpflug Imaging)
Prasanna Venkatesh Ramesh1, Prajnya Ray2, Aji Kunnath Devadas2, Shruthy Vaishali Ramesh3, Meena Kumari Ramesh3, Ramesh Rajasekaran4, Akshay Surendran2
1 Department of Glaucoma and Research, Mahathma Eye Hospital Private Limited, Trichy, Tamil Nadu, India
2 Department of Optometry and Visual Science, Mahathma Eye Hospital Private Limited, Trichy, Tamil Nadu, India
3 Department of Cataract and Refractive Surgery, Mahathma Eye Hospital Private Limited, Trichy, Tamil Nadu, India
4 Department of Paediatric Ophthalmology and Strabismus, Mahathma Eye Hospital Private Limited, Trichy, Tamil Nadu, India
| Date of Submission | 29-Dec-2021 |
| Date of Decision | 23-Mar-2022 |
| Date of Acceptance | 24-Mar-2022 |
| Date of Web Publication | 30-Jun-2022 |
Correspondence Address:
Prasanna Venkatesh Ramesh
Mahathma Eye Hospital Private Limited, No. 6, Seshapuram, Tennur, Trichy - 620 017, Tamil Nadu
India
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/tjosr.tjosr_188_21
How to cite this article:
Ramesh PV, Ray P, Devadas AK, Ramesh SV, Ramesh MK, Rajasekaran R, Surendran A. 'Bread Crumbs' of granular corneal dystrophy: Through the looking glass (Scheimpflug Imaging). TNOA J Ophthalmic Sci Res 2022;60:203-4 |
How to cite this URL:
Ramesh PV, Ray P, Devadas AK, Ramesh SV, Ramesh MK, Rajasekaran R, Surendran A. 'Bread Crumbs' of granular corneal dystrophy: Through the looking glass (Scheimpflug Imaging). TNOA J Ophthalmic Sci Res [serial online] 2022 [cited 2022 Aug 12];60:203-4. Available from: https://www.tnoajosr.com/text.asp?2022/60/2/203/349519 |
A 45-year-old male patient presented to the outpatient department with complaints of defective vision in both eyes (OU) and best corrected visual acuity of 20/60 in OU. Slit lamp examination [Figure 1]a and [Figure 1]b and anterior segment optical coherence tomography (AS-OCT) [Figure 1]c and [Figure 1]d were performed, and granular corneal dystrophy type 1 was diagnosed. This is a rare, slow-progressing, autosomal-dominant, bilateral, non-inflammatory, genetic dystrophy, which can eventually cause vision impairment because of gradual confluence and discomfort due to corneal erosion later in life.[1],[2],[3],[4],[5] In this manuscript, Scheimpflug imaging [Figure 2] of granular corneal dystrophy is presented, which has never been reported in the literature yet. | Figure 1: (a and b) Slit lamp examination revealing multiple, discrete, central, white-coloured sharply demarcated anterior stromal deposits resembling sugar granules or glass splinters, extending from the subepithelial layer to deep stroma. (c and d) Anterior segment optical coherence tomography (AS-OCT) showing the hyperreflective granular deposition with backshadowing (red arrows) of the granular opacities, extending from the subepithelial layer to deep stroma
Click here to view |
 | Figure 2: (a and b) Scheimpflug image revealing the topographic localization and the depth of the multiple granular corneal deposits in the form of hyperreflective and hyporeflective bread crumbs (red arrows) hotspots in both default and inverse colours, respectively, extending from the subepithelial layer to deep stroma
Click here to view |
Declaration of patient consent
The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient (s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.
Financial support and sponsorship
Nil.
Conflicts of interest
There are no conflicts of interest.
| References | |  |
| 1. | Lyons CJ, McCartney AC, Kirkness CM, Ficker LA, Steele ADM, Rice NSC. Granular corneal dystrophy: Visual results and pattern of recurrence after lamellar or penetrating keratoplasty. Ophthalmology 1994;101:1812-7.  |
| 2. | Lin Z-N, Chen J, Cui H-P. Characteristics of corneal dystrophies: A review from clinical, histological and genetic perspectives. Int J Ophthalmol 2016;9:904-13. |
| 3. | Mazzotta C, Traversi C, Baiocchi S, Barabino S, Mularoni A. Phenotypic spectrum of granular corneal dystrophy type II in two Italian families presenting an unusual granular corneal dystrophy type I clinical appearance. Case Rep Ophthalmol Med 2015;2015:703418. |
| 4. | Kodavoor SK, Deb B, Ramamurthy D. Deep anterior lamellar keratoplasty outcomes in macular and granular corneal dystrophy – A comparative cross-sectional study. Indian J Ophthalmol 2019;67:1830-3. [ PUBMED] [Full text] |
| 5. | Ramesh SV, Ramesh PV, K A, Ramesh MK, Rajasekaran R. Rare keratopathy of bilateral anterior amorphous corneal opacities with spontaneous corneal stromalysis and unilateral descemetocele-quantitative framing with AS-OCT and scheimpflug imaging in inverse contrast. J Surg Res 2021;4:301-7. |
[Figure 1], [Figure 2]
|
Search Pubmed for