• Users Online: 125
  • Print this page
  • Email this page


 
 Table of Contents  
OPHTHALMIC IMAGE
Year : 2022  |  Volume : 60  |  Issue : 2  |  Page : 203-204

'Bread Crumbs' of granular corneal dystrophy: Through the looking glass (Scheimpflug Imaging)


1 Department of Glaucoma and Research, Mahathma Eye Hospital Private Limited, Trichy, Tamil Nadu, India
2 Department of Optometry and Visual Science, Mahathma Eye Hospital Private Limited, Trichy, Tamil Nadu, India
3 Department of Cataract and Refractive Surgery, Mahathma Eye Hospital Private Limited, Trichy, Tamil Nadu, India
4 Department of Paediatric Ophthalmology and Strabismus, Mahathma Eye Hospital Private Limited, Trichy, Tamil Nadu, India

Date of Submission29-Dec-2021
Date of Decision23-Mar-2022
Date of Acceptance24-Mar-2022
Date of Web Publication30-Jun-2022

Correspondence Address:
Prasanna Venkatesh Ramesh
Mahathma Eye Hospital Private Limited, No. 6, Seshapuram, Tennur, Trichy - 620 017, Tamil Nadu
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/tjosr.tjosr_188_21

Rights and Permissions

How to cite this article:
Ramesh PV, Ray P, Devadas AK, Ramesh SV, Ramesh MK, Rajasekaran R, Surendran A. 'Bread Crumbs' of granular corneal dystrophy: Through the looking glass (Scheimpflug Imaging). TNOA J Ophthalmic Sci Res 2022;60:203-4

How to cite this URL:
Ramesh PV, Ray P, Devadas AK, Ramesh SV, Ramesh MK, Rajasekaran R, Surendran A. 'Bread Crumbs' of granular corneal dystrophy: Through the looking glass (Scheimpflug Imaging). TNOA J Ophthalmic Sci Res [serial online] 2022 [cited 2022 Nov 27];60:203-4. Available from: https://www.tnoajosr.com/text.asp?2022/60/2/203/349519



A 45-year-old male patient presented to the outpatient department with complaints of defective vision in both eyes (OU) and best corrected visual acuity of 20/60 in OU. Slit lamp examination [Figure 1]a and [Figure 1]b and anterior segment optical coherence tomography (AS-OCT) [Figure 1]c and [Figure 1]d were performed, and granular corneal dystrophy type 1 was diagnosed. This is a rare, slow-progressing, autosomal-dominant, bilateral, non-inflammatory, genetic dystrophy, which can eventually cause vision impairment because of gradual confluence and discomfort due to corneal erosion later in life.[1],[2],[3],[4],[5] In this manuscript, Scheimpflug imaging [Figure 2] of granular corneal dystrophy is presented, which has never been reported in the literature yet.
Figure 1: (a and b) Slit lamp examination revealing multiple, discrete, central, white-coloured sharply demarcated anterior stromal deposits resembling sugar granules or glass splinters, extending from the subepithelial layer to deep stroma. (c and d) Anterior segment optical coherence tomography (AS-OCT) showing the hyperreflective granular deposition with backshadowing (red arrows) of the granular opacities, extending from the subepithelial layer to deep stroma

Click here to view
Figure 2: (a and b) Scheimpflug image revealing the topographic localization and the depth of the multiple granular corneal deposits in the form of hyperreflective and hyporeflective bread crumbs (red arrows) hotspots in both default and inverse colours, respectively, extending from the subepithelial layer to deep stroma

Click here to view


Declaration of patient consent

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient (s) has/have given his/her/their consent for his/her/their images and other clinical information to be reported in the journal. The patients understand that their names and initials will not be published and due efforts will be made to conceal their identity, but anonymity cannot be guaranteed.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Lyons CJ, McCartney AC, Kirkness CM, Ficker LA, Steele ADM, Rice NSC. Granular corneal dystrophy: Visual results and pattern of recurrence after lamellar or penetrating keratoplasty. Ophthalmology 1994;101:1812-7.  Back to cited text no. 1
    
2.
Lin Z-N, Chen J, Cui H-P. Characteristics of corneal dystrophies: A review from clinical, histological and genetic perspectives. Int J Ophthalmol 2016;9:904-13.  Back to cited text no. 2
    
3.
Mazzotta C, Traversi C, Baiocchi S, Barabino S, Mularoni A. Phenotypic spectrum of granular corneal dystrophy type II in two Italian families presenting an unusual granular corneal dystrophy type I clinical appearance. Case Rep Ophthalmol Med 2015;2015:703418.  Back to cited text no. 3
    
4.
Kodavoor SK, Deb B, Ramamurthy D. Deep anterior lamellar keratoplasty outcomes in macular and granular corneal dystrophy – A comparative cross-sectional study. Indian J Ophthalmol 2019;67:1830-3.  Back to cited text no. 4
[PUBMED]  [Full text]  
5.
Ramesh SV, Ramesh PV, K A, Ramesh MK, Rajasekaran R. Rare keratopathy of bilateral anterior amorphous corneal opacities with spontaneous corneal stromalysis and unilateral descemetocele-quantitative framing with AS-OCT and scheimpflug imaging in inverse contrast. J Surg Res 2021;4:301-7.  Back to cited text no. 5
    


    Figures

  [Figure 1], [Figure 2]



 

Top
 
 
  Search
 
Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
Access Statistics
Email Alert *
Add to My List *
* Registration required (free)

 
  In this article
References
Article Figures

 Article Access Statistics
    Viewed428    
    Printed34    
    Emailed0    
    PDF Downloaded52    
    Comments [Add]    

Recommend this journal


[TAG2]
[TAG3]
[TAG4]