TNOA Journal of Ophthalmic Science and Research

CASE REPORT
Year
: 2021  |  Volume : 59  |  Issue : 3  |  Page : 270--272

Malady of lattice


Shobita Nair1, Venugopal Anitha1, Meenakshi Ravindran2, Vinit J Shah3 
1 Cornea and Refractive Services, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India
2 Paediatric and Strabismus Services, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India
3 Retina Services, Aravind Eye Hospital, Tirunelveli, Tamil Nadu, India

Correspondence Address:
Dr. Venugopal Anitha
Aravind Eye Hospital, S. N. High Road, Tirunelveli Junction, Tirunelveli - 627 001, Tamil Nadu
India

Lattice corneal dystrophy (LCD) is rare, bilateral, slowly progressive, inherited condition characterized by amyloid deposition in the corneal stroma. Recurrent corneal erosions most commonly occur with LCD due to abnormal basement membrane complexes incapable of providing normal structural integrity to the epithelial layer predisposing the cornea to microbial infections such as bacterial and fungal keratitis. Amyloid fibrils have also been postulated to cause tissue damage by stimulating local and nonlocal immune cell infiltration into the tissues and producing pro-inflammatory cytokines leading to sterile inflammation. This case is one of the few rare case reports of sterile infiltrates in LCD Type 1, patients identified after multiple treatment failures to the best of our knowledge.


How to cite this article:
Nair S, Anitha V, Ravindran M, Shah VJ. Malady of lattice.TNOA J Ophthalmic Sci Res 2021;59:270-272


How to cite this URL:
Nair S, Anitha V, Ravindran M, Shah VJ. Malady of lattice. TNOA J Ophthalmic Sci Res [serial online] 2021 [cited 2022 Jan 24 ];59:270-272
Available from: https://www.tnoajosr.com/article.asp?issn=2589-4528;year=2021;volume=59;issue=3;spage=270;epage=272;aulast=Nair;type=0